Tag Archives: Tyrocidine

Sequence Antibiotics

Tyrocidine B1, one of many antibiotics produced by Bacillus brevis. Tyrocidine B1 is defined by the 10 amino acid-long sequence shown below. Val-Lys-Leu-Phe-Pro-Trp-Phe-Asn-Gln-Tyr

proteinThe Central Dogma of Molecular Biology states that “DNA makes RNA makes protein.”amnioacid

Transcription simply transforms a DNA string into an RNA string by replacing all occurrences of T with U. The resulting strand of RNA is translated into an amino acid sequence via the genetic code; this process converts each 3-mer of RNA, called a codon, into one of 20 amino acids. As illustrated in the figure below, each of the 64 RNA codons encodes its own amino acid (some codons encode the same amino acid), with the exception of three stop codons that do not translate into amino acids and serve to halt translation. For example, the DNA string TATACGAAA transcribes into the RNA string UAUACGAAA, which in turn translates into the amino acid string Tyr-Thr-Lys. Read more of this post